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This time, we will summarize the most frequently asked information about NMN into one content, including NMN nutritional supplements , efficacy , effects , side effects , intake amount , and intake method .

• NMN Supplement

NMN (Nicotinamide mononucleotide) is a precursor to NAD+ and is converted into NAD+ when consumed in the body . NAD+ is one of the substances that helps maintain healthy youth in our body.

However , since NAD+ itself cannot be absorbed by the body, the most effective way to stay healthy and young is to take NMN and convert it into NAD+ in the body . David A. Sinclair, a pioneer in aging research at Harvard University, wrote about it in his book “ The End of Aging ” as his own secret to managing aging, and it has also been recognized as a representative antioxidant in Korea .

• NMN efficacy and effects

 NMN Efficacy , effect (1) Antioxidant, anti-inflammatory

Nowadays, people pursue maintaining a long and healthy life rather than simply living a long life . Therefore, the level of aging proteins generally increases rapidly at the ages of 34 , 60 , and 78 , and NMN is a substance that activates cells and lowers the level of aging proteins .

In conclusion, NMN restores the ability of damaged mitochondria to repair DNA and activates sirtuins, which are famous longevity genes, thereby enhancing immunity through antioxidant and anti-inflammatory effects.

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/info-nmn-supplements-effect

NMN efficacy and effects (2) Skin anti-aging

One study examined changes in various biomarkers in 17 Japanese female volunteers with an average age of 55 who took NMN (300 mg) once a day for 8 weeks .

Among them, subjects who took NMN for 8 weeks had a decrease in advanced glycation end products (AGEs), which is a result of skin autofluorescence , and as a result, skin autofluorescence (AF), which is an indicator of skin health, also decreased .

Since increased levels of AGEs are closely related to the progression of skin aging , this means that NMN is effective for skin health .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn_skin_health_thesis

NMN efficacy and effects (3) Diabetes prevention

One study involved 25 overweight and obese pre-diabetic female volunteers, ages 55 to 75 , who were divided into two groups: placebo (n=12) and NMN 250 mg (n=13) for 10 weeks .

As a result, we can see that the NMN 250 mg group had a glucose diaposal rate that was approximately 25% higher than the placebo group .

This suggests that combining insulin treatment with NMN for 10 weeks can help prevent diabetes .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn_diabetes_info_thesis

NMN efficacy and effects (4) Prevention of cardiovascular disease

One study measured vascular stiffness in healthy adults aged 40 to 59 years who took NMN for 12 weeks to investigate the effects of NMN on vascular health .

The key here is that as we age, the elasticity of our blood vessels decreases , so the stiffness of our blood vessels increases and our blood vessel health declines, so the possibility of preventing cardiovascular disease can be determined by the stiffness of our blood vessels .

Unlike placebo recipients, NMN recipients showed a positive effect on vascular health, as their pulse rate slowed and their vascular stiffness decreased on the left and right ankles.

If you would like more information, please refer to the link below.
Link : https://rokitamerica.com/blogs/blog/nmn_blood_vessel_thesis

NMN efficacy and effects (5) Deep sleep

In one study , 108 participants were divided into four groups ( placebo : morning , afternoon / NMN: morning , afternoon ) and each group took NMN (250 mg) or placebo once a day for 12 weeks to investigate the effects of NMN intake over time on sleep quality, fatigue, and physical ability in the elderly.

NMN users in the afternoon had significantly higher sleep duration and sleep quality scores compared to the other groups . This suggests that NMN intake may help with sleep .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn_sleep_thesis

NMN efficacy and effects (6) Improved kidney function

In one study, Wakino and colleagues at the University of Tokushima, Japan, administered 500 mg/kg/day of NMN for 2 weeks to investigate the effects of NMN on kidney function. To measure the improvement in kidney function, they measured the urinary protein-to-creatinine ratio (ACR) , a measure of urine protein levels, as high urine protein levels are linked to kidney damage and filtration impairment. They then compared this to the number of podocytes, which are needed for kidney waste filtration .

As a result , it was found that the number of podocytes in NMN consumers was higher than in the other groups .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn_kidney_health_thesis

NMN efficacy and effects (7) Infertility

Harvard scientists, including Professor Walter Wilett , author of “The Fertility Diet,” say that Nicotinamide mononucleotide, or NMN , may be effective in treating infertility .

For that reason, egg cells are vulnerable to DNA damage that progresses with age, but NMN is the most studied substance in aging and age-related diseases because it is converted to NAD+ in the body and helps repair DNA damage as proteins such as sirtuins and PARP .

In particular , Harvard Professor David A. Sinclair has documented a case report of an older woman who resumed menstruation after taking NMN during menopause , demonstrating that NMN may contribute to ovarian health, along with increased energy and metabolic activity .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn_infertility_effect_thesis

 NMN efficacy and effects (8) Muscle strength improvement

In one study, 42 Japanese male volunteers, with an average age of 65 years or older, took either a placebo (n=21) or 250 mg of NMN (n=21) for 12 weeks and had several health indicators measured .

As a result of comparing left hand grip strength , the NMN 250 mg group showed stronger left hand grip strength at weeks 6 and 12 compared to the placebo group .

Although the study has limitations in that there was no significant change in right-hand grip strength , the researchers speculate that since 90% of the Japanese population is right-handed, the effects of NMN supplementation may be more pronounced in the left hand, which is less affected by daily exercise and movement .

If you would like more details , please refer to the link below .
Link : https://rokitamerica.com/blogs/blog/nmn-muscle-improvement

• NMN side effects

NMN has been reported to be a safe substance with few side effects to date.

However, there are concerns that excessive intake of NMN can cause vomiting and flushing, as well as increase blood vessel formation and blood flow, which can contribute to cancer growth. However, Professor David of Harvard University, author of " The End of Aging," mentioned above, says that maintaining an appropriate intake of NMN can actually restore vascular health.

• NMN intake and method of intake

NMN Dosage and method of intake (1) NMN intake

There are various preclinical studies on NMN intake ranging from 250 mg to 1000 mg per day , but more than 70% of studies on NMN used 250 mg of NMN intake.

NMN intake and method of intake (2) NMN intake method

NMN is a water-soluble nutrient, so it is recommended to take it on an empty stomach , about an hour before breakfast . However, this may vary depending on each person's physical condition , so if taking it on an empty stomach is difficult , you can also take it after a meal .

We've compiled and briefly covered the most frequently asked questions about NMN .

If you are interested in a detailed paper on the content, please refer to the link at the bottom of each content .

We will continue to introduce new papers and research results on NMN through the Rocket America blog .

ROKIT America NMN Long-Lasting Silver

It is easy to adjust the intake amount according to needs , and the capsule size is small.

This product is formulated to be easy on the throat .

About ROKIT America NMN Long-Lasting

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We will come back with more useful health information next time .

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