Why Rocket America Fisetin?
What is FISETIN?
Fisetin is a polyphenol compound of the flavonoid family, and is found in various fruits and vegetables, including strawberries , apples , persimmons , and lotus roots, at concentrations ranging from 0.1 to 160 μg/g . Strawberries, in particular, contain 160 μg/g of fisetin . ( To obtain the 100 mg of fisetin contained in Rocket America, you would need to eat about 52 strawberries .)
Fisetin has been demonstrated in research papers to be a promising drug for treating various diseases, including anti-tumor and anti-inflammatory activities. Its potential mechanisms of action include treating neurological disorders such as Alzheimer's disease, Parkinson's disease, and traumatic brain injury, as well as periodontitis, hypertrophic scarring, oxidative skin damage, polycystic ovary syndrome (PCOS), osteoporosis, heart disease, diabetic cardiomyopathy, high-fat diet-induced nephropathy, and hypercholesterolemia.
Fisetin is also considered the " most potent senolytic substance " among polyphenols . Preclinical studies have demonstrated that fisetin 's senolytic properties can slow down aging .
*Senolytic = Senescence (aging) + lytic (destroy)
What makes Rocket America Fisetin so special?
1. Rocket America's unique blend with a reason!
Meanwhile, fisetin is an insoluble substance that does not dissolve well in water and tends to clump together with oils. Numerous studies have reported that when fisetin is consumed alone, its absorption efficiency in the body is low. To overcome fisetin's low oral bioavailability (44.1%) due to its low water solubility (10.45 g/mL), Rocket America researched an improved formulation.
POINT 1. Use of BioPerine®, a patented substance that increases the absorption rate of fisetin.
Bioperine is a patented substance that improves nutrient absorption by at least 30% when consumed in the recommended 5mL dose . Rocket America has enhanced the bioavailability of fisetin by incorporating Bioperine and further reducing the particle size.
As you can see from the above experiment, Rocket America's scientific mixing ratio and finer particle size have resulted in an increased 'absorption rate'.
POINT 2. Combination of ascorbic acid and vitamin C with fisetin
We also added ascorbic acid vitamin C, which can help increase the cancer cell proliferation inhibition effect of fisetin . A study showed that taking fisetin and vitamin C together inhibited cancer cell proliferation by 61% .
2. Uses 99% pure fisetin!
Rocket America uses raw materials containing a whopping 99% pure fisetin, the main ingredient. As of June 2024, the newly verified 99% purity results demonstrate the highest purity among existing fisetin products.
▲ Among the purity test results from Certified Laboratories
"High purity" means that the product has been thoroughly purified, removing impurities and unnecessary substances. Even when taking the same dosage of a nutritional supplement, choosing a product with higher purity allows you to consume more of the nutrients you need. Furthermore, higher purity means less unpleasant odor and less gastrointestinal upset. We strongly recommend considering the importance of "purity" when choosing a nutritional supplement.
3. Vegetable capsules without chemical additives!
Rocket America Fisetin's vegetable capsules are made from natural rice bran extracts without chemical additives, and are developed to be less burdensome to the human body and dissolve better than animal-based capsules.
4. Manufactured under safe and thorough quality control!
You can take Rocket America Fisetin with confidence because it is safely and thoroughly produced in a manufacturing facility approved by the US FDA .
References and Sources
[1] Fisetin—In Search of Better Bioavailability—From Macro to Nano Modifications: A Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10532335/
[2] Emerging novel drug delivery strategies for bioactive flavonol fisetin in biomedicine: https://pubmed.ncbi.nlm.nih.gov/30119198/
[3] Ascorbic acid-enhanced antiproliferative effect of flavonoids on squamous cell carcinoma in vitro: https://pubmed.ncbi.nlm.nih.gov/8457720/
[4] How to calculate the true purity of Omega-3 as explained by a pharmacist: https://aimee.kr/magazine/42
[5] Fisetin absorption rate comparison video: https://smartstore.naver.com/rokitamerica/shoppingstory/detail?id=2002667495&page=6
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