hello .
In this lesson, we will look at NMN and its safe content .

• NMN

Nicotinamide mononucleotide (NMN) is an orally bioavailable NAD+ precursor that has been shown to have beneficial effects on aging and age-related diseases . As we age, NAD+ levels decrease, but preclinical studies have shown that when NMN is consumed , it is converted to NAD+ in the body, which can improve diseases of aging such as obesity , diabetes , heart failure , stroke , kidney failure, and Alzheimer's disease .
Let's find out how much NMN is safe for humans to consume to improve these various aging diseases, based on clinical trial results .

• How many mg of NMN is safe ?

Based on a paper published in April 2022 , we will inform you about the side effects of NMN and the safe amount for humans .

In this study, we randomly assigned a placebo group to NMN intake to investigate the safety of oral intake of NMN and its efficacy in increasing NAD+ concentrations . Thirty Japanese volunteers with an average age of 43 took either a placebo (n=15) or 250 mg of NMN (n=15) daily for 12 weeks .

Copyright © 2022 Okabe, Yaku, Uchida, Fukamizu, Sato, Sakurai, Tobe, Nakagawa.

The first thing that was noticed in the study was whether there were any side effects .
Comparing the placebo group and the NMN intake group , both groups had normal liver , kidney , and blood values , and no significant side effects were observed .

Copyright © 2022 Okabe, Yaku, Uchida, Fukamizu, Sato, Sakurai, Tobe, Nakagawa.

In addition , when we examined NAD+ and related metabolites in the whole blood of the placebo and NMN intake groups during the experiment , the NAD+ concentration in the whole blood significantly increased, unlike the placebo group, at weeks 4 , 8 , and 12 of NMN intake . However, at week 16 , 4 weeks after stopping NMN intake, the NAD+ concentration in the NMN intake group returned to a level similar to that of the placebo group .
This paper suggests that a steady intake of 250 mg of NMN per day can maintain NAD+ levels in the body without adverse effects, and demonstrates that 250 mg is a safe amount of NMN.

 

This time with NMN
Learn about the safe dosage of NMN .

 

Rocket America NMN is
Comply with the safe content of 250mg of NMN,
Combined with pterostilbene to increase NAD+ concentration by increasing absorption in the body.
About Rokit America NMN
Click on the picture below to see more information about that product.

Here's more useful information
I'll come back with more content .

 

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[ Reference material ]
[1] Okabe K, Yaku K, Uchida Y, Fukamizu Y, Sato T, Sakurai T, Tobe K, Nakagawa T. Oral Administration of Nicotinamide Mononucleotide Is Safe and Efficiently Increases Blood Nicotinamide Adenine Dinucleotide Levels in Healthy Subjects. Front Nutr. 2022 Apr 11;9:868640. doi: 10.3389/fnut.2022.868640. PMID: 35479740; PMCID: PMC9036060.