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[Highlight] "Feeding NMN to ALS mice extends their lifespan by about 3.5%. The onset of motor dysfunction is delayed and signal transmission from nerves to muscles is preserved."   0. Amyotrophic lateral sclerosis Amyotrophic lateral sclerosis ( ALS ) is a neurodegenerative disease characterized by the degeneration of motor neurons in the motor cortex of the brain and spinal cord. Commonly known as Lou...