[Health Information] How Eye Care Protects Eye Health

Since eye diseases do not have clear symptoms in the early stages, it is important to prevent them in advance and maintain eye health . We would like to introduce the efficacy of each ingredient in Rocket America's 'EYE CARE' product and how EYE CARE nutritional supplements prevent eye diseases and help with eye health .
How does EYE CARE protect eye health?

EYE CARE contains Bilberry Extract (80mg) , Pycnogenol (40mg), Lutein (20mg), Zeaxanthin (4mg), Astaxanthin (6mg), Vitamin A (500mcg RAE), Vitamin C (200mg), Zinc (25mg), Copper (2mg), Vegetable Capsules .
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Bilberry extract + Pycnogenol complex Intraocular pressure relief action
The experimental group treated with Mirtogenol, a combination of bilberry extract and pycnogenol, showed a statistically significant difference compared to the control group. The IOP (intraocular pressure) of the control group did not significantly deviate from 24 mmHg to 25 mmHg . Mirtogenol is There was a steady decrease from about 25 mmHg to about 22 mmHg . This proves the intraocular pressure-relieving effect of the combination of bilberry extract and pycnogenol.
Especially 2 months From the above, there is a big difference compared to the control group, which is at least for 2 months. This means that if you consume it consistently, you can achieve meaningful changes in your eye health.
Glaucoma is It is a disease that can lead to blindness due to damage to the optic nerve of the retina. The most dangerous factor among the causes of optic nerve damage is increased intraocular pressure . Therefore, taking Pycnogenol and bilberry extract together, which are effective in preventing increased intraocular pressure and improving eye health, can help prevent glaucoma. It may have a preventive effect.

Additionally, data supporting the intraocular pressure-reducing effects of bilberry extract and pycnogenol are available. Ophthalmologist, University of Chieti-Pescara, Italy As a result of a clinical study conducted by Professor Steigerwalt's research team, High intraocular pressure of 25 mmHg or more on average For patients with glaucoma IN DENA Bilberry extract and When HORPHAG's Pycnogenol was administered, it was confirmed that the intraocular pressure (IOP) dropped from 38.1 mmHg to 29.0 mmHg after 16 weeks, and it was confirmed that the IOP value improved and the blood flow velocity of the retinal artery increased .
Lutein + Pycnogenol for retinal disease
Lutein + Pycnogenol Complex Antioxidant effects on retinal lipids
The eye is made up of a lipid barrier that protects the retina . The retina is the tissue with the highest metabolic rate in the body and is a site of high oxidative stress . Furthermore, ocular tissue is exposed to strong ultraviolet rays that generate reactive oxygen species . When the retina experiences extreme oxidative stress under various conditions, retinal diseases can occur .
So how can we prevent oxidation in the retinal lipids ?
*Retina: Nerve tissue located at the back of the eye

|
Lutein / Pycnogenol |
Before processing |
After processing |
|
FeCl 3 |
12 μ g/mL |
5 μ g/mL |
|
AAPH |
2.8 μ g/mL |
0.5 μ g/mL |
|
AMVN |
465 μ g/mL |
110 μ g/mL |
When FeCl 3 , AAPH, and AMVN are treated to the retinal fluid of pigs , lipid oxidation is induced, which resembles a state in which retinal disease has occurred . When lutein and pycnogenol are treated together , FeCl 3 drops from 12 μg/mL to 5 μg/mL, AAPH decreases from 2.8 μg/mL to 0.5 μg/mL , and AMVN decreases from 465 μg/mL to 110 μg/mL . This confirms that the degree of lipid oxidation is reduced and that lutein and pycnogenol have antioxidant effects .

Furthermore, we will specifically examine how much more powerful the antioxidant capacity of a combination of lutein and pycnogenol is than the antioxidant capacity of lutein and pycnogenol alone . While lutein and pycnogenol each have strong antioxidant capacity, we were able to find that when lutein and pycnogenol are combined and consumed together, they have an additional 60% retinal lipid antioxidant effect compared to when consumed separately .
Taking a combination of lutein and pycnogenol can be very helpful in preventing retinal diseases because it strongly inhibits oxidation of retinal lipids .
Lutein + Zeaxanthin for macular degeneration
Lutein + Zeaxanthin Complex Maintaining macular pigment density
The macula is the area in charge of the central vision of the eye, and macular pigment exists in it . This macular pigment plays a role in absorbing blue light . The problem is that as we pass our 20s and 30s , our eyes are exposed to blue light for a long time, and it accumulates, and as it is also greatly damaged by ultraviolet rays, the density of macular pigment decreases rapidly . As a result, macular degeneration can occur . How can we prevent the decline of macular pigment ?
* Macula: The area in the center of the retina where light focuses and receives visual information and sends it to the brain, allowing us to recognize objects.

AREDS2 formulation
I would like to introduce the 'AREDS2 study (Age Related Eye Disease Study 2),' a representative study on age-related macular degeneration . The ' National Eye Institute' conducted a large-scale clinical study for 5 years with 4,203 patients with age-related macular degeneration, and had the patients consistently consume lutein , zeaxanthin , vitamins C and E, etc. As a result , it was proven that lutein and zeaxanthin are representative ingredients that have an effect in slowing down macular degeneration .
As macular pigment decreases with age, it cannot be synthesized in the body, so it is necessary to supplement with lutein or zeaxanthin from outside sources to reduce the risk of developing macular degeneration .
Astaxanthin's Improves eye fatigue
As the use of electronic devices such as smartphones increases, the number of people complaining of eye fatigue is increasing . Astaxanthin is a powerful antioxidant that helps improve eye fatigue , eye accommodation , and ocular blood flow, and can be effective in treating various eye diseases .

Astaxanthin is the most powerful antioxidant among the carotenoid family . Its high hydrophobicity and ability to bind to cell membranes give it a particularly strong antioxidant effect compared to other carotenoids . As an antioxidant, astaxanthin is highly effective in alleviating eye fatigue .
Preparing in advance for healthy eyes
'EYE CARE' is with you!
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[References and image sources ]
[5] Beneficial effects of picnogenol® on vision
[6] Lutein + Zeaxanthin and Omega-3 Fatty Acids for Age-Related Macular Degeneration
The Age-Related Eye Disease Study 2 (AREDS2) Randomized Clinical Trial, JAMA. 2013;309(19):2005-2015. doi:10.1001/jama.2013.4997
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